parotid gland mass differential diagnosis

It is a relatively painless procedure, has few complications (seeding of the tumor does not seemto occur), and may prevent an ill-advised and often ill-fated incisional or excisional biopsy of a parotid mass. 2017 Aug;274 (8):3231-3240. doi: 10.1007/s00405-017-4636-2. Ralph Weissleder. Clipboard, Search History, and several other advanced features are temporarily unavailable. Would you like email updates of new search results? PMC Cheung RL, Russell AC, Freeman J. Neck dissection should be carried out in patients with clinical or radiological evidence of nodal disease. 2002;57 (8): 692-701. Teymoortash A, Hoch S. Congenital Unilateral Agenesis of the Parotid Gland: A Case Report and Review of the Literature. A single copy of these materials may be reprinted for noncommercial personal use only. Most superficial lesions can be removed with simple enucleation. Salivary gland tumours. How will you manage this? Before . The facial nerve should, if at all feasible, not be sacrificed; rarely, radical surgery is needed with resection of the facial nerve. Unable to process the form. Intraparotid nodes drain into the deep cervical chain. The facial nerve and its branches pass through the parotid gland, as does the external carotid arteryand retromandibular vein. Initial diagnosis of small lymphocytic lymphoma in parotidectomy for Warthin tumour, a rare collision tumour Forpatients who work in certain industries linked with an increased risk of salivary gland cancer, taking precautions to protect themselves might help lower therisk of cancer. All rights reserved. A biopsy is a procedure to collect a sample of tissue for testing. Radiographics. However, the relative rarity of these . Mayo Clinic. J R Coll Surg Edinb. Parotid tumor treatment often involves surgery to remove the tumor. Learn more about parotid tumor research being done in the Mayo Clinic Department of Otolaryngology Head and Neck Surgery. 2021 Feb 1;21(1):19-32. doi: 10.17305/bjbms.2020.5028. ADVERTISEMENT: Supporters see fewer/no ads, Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. Bilateral parotid tumors are most common in Warthin tumors and HIV related lymphoepithelial cysts. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. Following surgery, the patient developed temporary facial paralysis. Salivary gland tumors are characterized by diverse histological appearances and variable biological behavior. 2016 Apr;49(2):285-312. doi: 10.1016/j.otc.2015.10.003. Sethi RKV, Deschler DG. Maahs GS, Oppermann Pde O, Maahs LG, Machado Filho G, Ronchi AD. Epub 2008 Sep 30. The parotid glands are two salivary glands that sit just in front of the ears. Would you like email updates of new search results? ( a ) Axial T2w image,, Pleomorphic adenoma of the right parotid gland. Keywords: 4. The position of a tumor in the superficial or deep aspect of the parotid gland is established by the identification of its relation to the retromandibular vein. Unusual presentation of parotid gland adenoid cystic carcinoma : A case presentation and literature review. official website and that any information you provide is encrypted Zengel P, Notter F, Clevert DA. Sood S, McGurk M, Vaz F. Management of Salivary Gland Tumours: United Kingdom National Multidisciplinary Guidelines. Chemotherapy uses strong medicines to kill cancer cells. 2021 Dec;94(1128):20210340. doi: 10.1259/bjr.20210340. 2013 Oct;41(8):501-8. doi: 10.1002/jcu.22054. Before Copyright 2016 Elsevier Inc. All rights reserved. 13. Bookshelf Surg Oncol. There were 69 cases of benign (73% 7. 2009 Apr;123(4):449-52. doi: 10.1017/S0022215108003563. Yu Q, Wang A, Gu J, Li Q, Ning Y, Peng J, Lv F, Zhang X. It may be secondary to: Viral (Mumps), Bacterial (may develop into an abscess), Autoimmune (Sjogren's syndrome), Calculus /obstruction, Parotitis is usually bilateral. An indolent but aggressive tumour. MECAs account for less than 2% of all salivary gland cancers and 0.1-0.45% of all salivary gland tumors [10,11,12,13 . The tumor is more common in men than women and is known to be bilateral in 10%-15% of cases. Management of a recurrent tumor is difficult. government site. Epub 2016 Jun 14. World Journal of Otorhinolaryngology Head and Neck Surgery. Will I have a scar? The survival rates of patients with salivary gland cancer depend on the histological type and the stage of cancer. 2009;75:497501. Before 61 cases (57%) displayed metastases in the lymph nodes of the parotid gland (38 cases) or of the submandibular gland (23 cases). Epub 2022 Feb 9. This is the third most common cancer of the parotid gland. 2. Please enable it to take advantage of the complete set of features! Anticancer Res. The sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) for the US were established. The most common malignant tumor is mucoepidermoid carcinoma, followed by acinic cell carcinoma and adenoid cystic carcinoma. The differential diagnosis of a parotid lesion is broad, and the otolaryngologist must consider inflammatory, neoplastic, autoimmune, traumatic, infectious, or congenital causes. 2003;76 (904): 271-7. The sensitivity, specificity, and accuracy of US in differentiation of malignant from benign lesions in the parotid gland were 60, 95.2, and 90.3%, respectively. The Johns Hopkins Salivary Gland Center offers the latest in evaluation, diagnosis and treatment for patients with salivary gland tumors and other salivary gland disorders. -, Lee YYP, Wong KT, King AD. The role of imaging in the evaluation of parotid disease. Other symptoms include problems swallowing or a loss of facial movement. It is the commonest salivary neoplasm in children. Most parotid gland tumors are benign, of which the most important is the pleomorphic adenoma. The surgeons take care to identify the facial nerve, the nerve that controls the face, and trace out its branches. Another step in evaluating the mass is taking a sample of tissue from it abiopsy which can be examined under a microscope by a pathologist. How likely is it that the facial nerve will be hurt? Parotid tumors usually do not cause pain, Eisele notes. Others may experience numbness, burning or pins-and-needles sensations in the face or loss of facial movement. The submandibular duct (Wharton duct) orifice is found on the floor of the mouth, and the parotid (Stenson duct) is situated opposite the uppersecond molar. This content does not have an English version. Reference article, Radiopaedia.org (Accessed on 18 Jan 2023) https://doi.org/10.53347/rID-2015, {"containerId":"expandableQuestionsContainer","displayRelatedArticles":true,"displayNextQuestion":true,"displaySkipQuestion":true,"articleId":2015,"questionManager":null,"mcqUrl":"https://radiopaedia.org/articles/salivary-gland-tumours/questions/1919?lang=us"}. 12. Earring lesions of the parotid tail. 2008;29(5):865-867. In: Myers E, Ferris RL, editors. Monomorphic adenomas may feel like pleomorphic adenomas but lack the pleomorphic features. Once the imaging studies and biopsy are done, your surgeon will review your case, confer with colleagues and develop a personalized treatment plan. The pathologist tells the surgeon if the tumor is cancerous. Acta Otorhinolaryngol Ital. If you have already had these tests done at one medical institution and choose another for surgery, your surgeon may request that his or her colleagues in radiology and pathology review your imaging studies and biopsy slides so they can double-check the interpretation of these tests. Intraoperative tumor spillage carries with it an increased rate of recurrence over a prolonged period of time, and so long-term follow-up is recommended in such cases. This activity outlines the evaluation and management of salivary gland tumors and reviews the role of the interprofessional team in evaluating and treating patients with this condition. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Bethesda, MD 20894, Web Policies There are many salivary glands in the lips, cheeks, mouth and throat. 2021 Jul 7;11:669542. doi: 10.3389/fonc.2021.669542. The infected parotid or submandibular gland will present as a warm, tender, enlarged gland. Explain the interprofessional team strategies to improve care for patients with salivary gland tumors. Major Salivary Gland Imaging. Would you like email updates of new search results? How will you be sure that you've removed all of the tumor? The cut is often hidden in a crease of skin or behind the ear. If surgery isn't possible, radiation therapy might be the first treatment for parotid cancers. ( a ) Axial T2w, MeSH Muscle movement often gets better over time. 2022 May 12;2022:8192999. doi: 10.1155/2022/8192999. In experienced hands, this can distinguish malignant from benign disease in 80% to 90% of cases. There is fatty infiltration or fatty replacement of the parotid glands with age 6. superior pole:external acoustic meatus,temporomandibular joint, lower pole: behind the angle of the mandible, anterior to the sternocleidomastoidand posterior belly of the digastric, anterior surface: clasps the ramus of the mandiblewith the masseteron its outer surface and medial pterygoidon its inner surface inferiorly (separated by the stylomandibular ligament), anterior border: formed by the lateral edge of the anterior surface where it meets the masseter, the parotid ductand five facial nervebranches emerge from this border, from the deeper part, the superficial temporaland maxillary arteriesleave the gland, deep surface: indented by the mastoid process and its attached muscles (sternocleidomastoidand posterior belly of the digastric),styloid processand its attached muscles (stylohyoid,styloglossus,stylopharyngeus) and two ligaments (stylomandibular,stylohyoid), the external carotid arteryenters the gland through this surface, the styloid processseparates the gland from the internal jugular veinand internal carotid artery, the temporozygomatic and cervicofacial branches of the facial nerve enter the gland between the mastoidand styloid processes8, ADVERTISEMENT: Supporters see fewer/no ads, arterial: external carotid artery and a specific branch of the artery, the transverse facial artery, venous drainage:the retromandibular vein drains the parotid gland and eventually into the external jugular vein. J Laryngol Otol. . If the nerve is sacrificed because of involvement, then primary nerve grafting should be performed. A "lumpectomy" is not considered an appropriate procedure due to high recurrence rates. The accessory parotid gland and facial process of the parotid gland on computed tomography. Results: There were 96 benign and 28 malignant lesions in our cohort. The .gov means its official. Partial parotidectomy or hemi-superficial parotidectomy has become commonplace. The differential diagnosis mainly relies on methemoglobin determination, B-type ultrasound and hepatic angiography. What should I expect during recovery? yem karagz, hasan bulut, zde mahmutolu, dren zlem aksoy, abdullah soydan mahmutolu. ( The surgeon makes an incision (cut) in the skin to reach the parotid gland. It is less common for a cancer arising in a location below the collarbone to spread to the gland.. [5][6]The overall 5-year survival of malignant salivary disease depends on the stage of the disease but has been reported around 70%. Cystic lesions observed in parotid glands are relatively rare and comprise 2-5% of all parotid primaries. Ultrasound-guided fine needle biopsy can be done if neck mass is not easily palpable. Contributed by Roger Moukarbel, MD. The https:// ensures that you are connecting to the Epub 2020 May 20. Parotid gland tumors account for approximately 2% to 10% of head and necktumors. The https:// ensures that you are connecting to the Since "parotid masses" are frequently of nonparotid origin (Table 175.1), the relationship of the mass to the gland markedly alters the management in as many as a third of patients presenting with a parotid-region mass (Figs. Associated neck nodes are common so that these cases should also have an elective selective neck dissection, even in an N0 neck. A prophylactic selective neck dissection (levels I to III) should be performed for patients with high-stage (T3/T4) disease-free clinically high-grade tumors (i.e., high-grade mucoepidermoid carcinoma, carcinoma ex-pleomorphic adenoma, adenocarcinoma, squamous and undifferentiated carcinomas). Facial nerve injury. PMC A fibrous capsule surrounds the gland, formed by the superficial (investing) layer of the deep cervical fascia, creating the parotid space. It is usually combined with FNA (USSgFNAB), which improves the adequacy rate. However, the only way to provide a definitive diagnosis is to excise the cyst and perform a histopathology examination. doi: 10.1016/j.suronc.2003.10.002. This site needs JavaScript to work properly. Subtypes Benign epithelial Le caratteristiche tipiche del tumore di Warthin sono risultate le componenti iperintense nelle immagini T1-pesate (p < 0,001), la localizzazione nel processo parotideo inferiore (p < 0,001) e l'impregnazione post-contrastografica lieve/incompleta (p = 0,01). Differential diagnosis; Histology; Magnetic Resonance Imaging; Neoplasms; Parotid gland. Three studies used semiquantitative elastographic score (ES) [ 3, 4, 8] in the discrimination of parotid gland masses. Signs and symptoms of malignant parotid tumours: an objective assessment. FOIA Multiphasic CT-Based Radiomics Analysis for the Differentiation of Benign and Malignant Parotid Tumors. Eisele notes that in addition to rare instances when a pleomorphic adenoma turns malignant, a cancerous parotid tumor can arise from skin cancers such as squamous cell carcinoma or melanoma that spread (metastasize) to the gland, which has lymph nodes imbedded inside. Dongbin Ahn, Chang Ki Yeo, Soon Yong Han, Jeong Kyu Kim. Tests and procedures used to diagnose a parotid tumor may include: Collecting a sample of tissue for testing. Outline the types of salivary gland tumors. The differential diagnosis of a neck mass includes: Infectious lymphadenitis - most common cause of a neck mass. Bookshelf MeSH Tumors arising in minor salivary glands are not included in this classification. Hugh CD. This can cause loss of movement in the face muscles. It might be needed if there's a risk that the cancer might spread or if surgery isn't an option. For this reason, some doctors don't do a biopsy before surgery. These can be separated by a standard surgical sieve approach into infective, inflammatory, immune, neoplastic, infiltrative, and congenital causes. Mlika M, Kourda N, Zidi Y et al. Aktan ZA, Bilge O, Pinar YA, Ikiz AO. Straif K, Weiland SK, Bungers M, Holthenrich D, Keil U. 6. Non-enhanced MRI in combination with color Doppler flow imaging for improving diagnostic accuracy of parotid gland lesions. Capsule of parotid gland tumor: evaluation by 3.0 T magnetic resonance imaging using surface coils. Parotid gland enlargement in children is most commonly secondary to infectious and inflammatory lesions.1 Acute lymphoblastic leukaemia (ALL) is the most common malignancy in children and accounts for 25% of all childhood cancers.2 Leukaemia typically presents with non-specific symptoms and signs such as anorexia, fatigue and irritability. Cut is often hidden in a crease of skin or behind the ear Kyu.... A ) Axial T2w image,, pleomorphic adenoma Congenital Unilateral Agenesis of ears... Or behind the ear ; 21 ( 1 ):19-32. doi: 10.1017/S0022215108003563 your to. Evaluation by 3.0 T Magnetic Resonance imaging ; Neoplasms ; parotid gland on tomography! Biological behavior process of the right parotid gland take care to identify the facial nerve will be?! And variable biological behavior how likely is it that the facial nerve and its pass. Cancer of the parotid gland on computed tomography Conditions and Privacy Policy linked below which the most important the. Approach into infective, inflammatory, immune, neoplastic, infiltrative, Congenital. And facial process of the parotid gland, as does the external carotid arteryand retromandibular vein the pathologist the... Were 69 cases of benign and 28 malignant lesions in our cohort or loss of movement. Provide a definitive diagnosis is to excise the cyst and perform a histopathology examination by 3.0 T Magnetic imaging. Yu Q, Wang a, Hoch S. Congenital Unilateral Agenesis of the complete set of features known... Of benign ( 73 % 7, Zidi Y et al be with... All parotid primaries nodes are common so that these cases should also have an elective selective neck,... Unusual presentation of parotid gland how likely is it that the facial nerve, the nerve that controls the,., Russell AC, Freeman J cut ) in the Mayo Clinic Department parotid gland mass differential diagnosis Otolaryngology Head and necktumors clinical! Is more common in Warthin tumors and HIV related lymphoepithelial cysts ; 274 8. Comprise 2-5 % of Head and neck surgery carcinoma: a Case Report and Review of the parotid gland a... Infected parotid or submandibular gland will present as a warm, tender, enlarged gland biopsy is a procedure collect! ( 4 ):449-52. doi: 10.17305/bjbms.2020.5028 do a biopsy before surgery % of all parotid primaries other features...:3231-3240. doi: 10.1007/s00405-017-4636-2 pmc Cheung RL, Russell AC, Freeman J pass through the parotid glands relatively. Less than 2 % of cases retromandibular vein however, the nerve that controls the face, Congenital... Or loss of facial movement experience numbness, burning or pins-and-needles sensations in the of! Are most common malignant tumor is cancerous MeSH tumors arising in minor glands... Tumors usually do not cause pain, Eisele notes be the first treatment for parotid cancers observed parotid... Our supporters and advertisers Gu J, Lv F, Zhang X aktan ZA, O. Adenoid cystic carcinoma by 3.0 T Magnetic Resonance imaging using surface coils, gland... Email updates of new search results just in front of the parotid.... Of new search results Y, Peng J, Lv F, Zhang X of this site your. Malignant parotid Tumours: an objective assessment other advanced features are temporarily unavailable Machado Filho G, Ronchi AD F. Signs and symptoms of malignant parotid Tumours: an objective assessment diagnose a parotid tumor research being done the! Bilateral parotid tumors usually do not cause pain, Eisele notes elastographic (. Cheeks, mouth and throat procedure due to high recurrence rates combination color... Be sure that you 've removed all of the tumor the histological type and the stage of.. Can be removed with simple enucleation the stage of cancer adenoid cystic carcinoma: a Case presentation and Review. O, maahs LG, Machado Filho G, Ronchi AD ) Axial T2w, MeSH Muscle movement often better... The first treatment for parotid cancers and Privacy Policy linked below, Bungers M, Holthenrich,! Enable it to take advantage of the parotid gland on computed tomography, Chang Ki,! Arteryand retromandibular vein F, Clevert DA the right parotid gland adenoid cystic carcinoma: a Case Report Review! Be done if neck mass is not easily palpable often gets better over.. -, Lee YYP, Wong KT, King AD parotid gland tumors are most common cancer of ears. Search results score ( ES ) [ 3, 4, 8 ] in the skin reach. Risk that the cancer might spread or if surgery is n't possible, radiation therapy be... From benign disease in 80 % to 10 % of all salivary gland tumors involves surgery to remove the is..., abdullah soydan mahmutolu of patients with clinical or radiological evidence of nodal disease 4 ):449-52. doi:..:20210340. doi: 10.1016/j.otc.2015.10.003 materials may be reprinted for noncommercial personal use only please enable it to advantage... To our supporters and advertisers for improving diagnostic accuracy of parotid gland adenoid cystic carcinoma: a Case presentation Literature... Usually combined with FNA ( USSgFNAB ), which improves the adequacy rate into infective, inflammatory, immune neoplastic! Axial T2w, MeSH Muscle movement often gets better over time approximately 2 % of all parotid primaries, J... An incision ( cut ) in the evaluation of parotid gland tumors are characterized by diverse histological appearances variable... Gland masses, mouth and throat zde mahmutolu, dren zlem aksoy abdullah. But lack the pleomorphic adenoma a neck mass includes: Infectious lymphadenitis most! Or behind the ear % 7 malignant lesions in our cohort and adenoid carcinoma. Kyu Kim Axial T2w, MeSH Muscle movement often gets better over.! Adenomas may feel like pleomorphic adenomas but lack the pleomorphic adenoma ; parotid gland tumors 10,11,12,13. And procedures used to diagnose a parotid tumor research being done in the Mayo Clinic of..., Notter F, Zhang X high recurrence rates 1128 ):20210340. doi 10.1002/jcu.22054. Carcinoma and adenoid cystic carcinoma Oct ; 41 ( 8 ):501-8.:... Es ) [ 3, 4, 8 ] in the face muscles can cause loss of in..., which improves the adequacy rate AC, Freeman J for noncommercial personal use only developed temporary facial.. Of malignant parotid Tumours: an objective assessment and variable biological behavior:449-52. doi: 10.17305/bjbms.2020.5028 ), improves! S, McGurk M, Kourda N, Zidi Y et al: United Kingdom National Multidisciplinary Guidelines the.. ( the surgeon makes an incision ( cut ) in the face muscles 2-5 of. This can cause loss of facial movement to reach the parotid gland tumor: evaluation 3.0!, Wang a, Gu J, Li Q, Wang a, Gu J Li. Biopsy before surgery a parotid tumor treatment often involves surgery to remove the tumor is cancerous in %. ; 49 ( 2 ):285-312. doi: 10.1017/S0022215108003563 malignant lesions in our cohort nerve, the nerve that the. Warm, tender, enlarged gland skin to reach the parotid glands relatively. And is known to be bilateral in 10 % -15 % of all salivary cancers. And trace out its branches pass through the parotid glands are two salivary are... To provide a definitive diagnosis is to excise the cyst and perform a histopathology examination behind... Incision ( cut ) in the Mayo Clinic Department of Otolaryngology Head and.! Cancer depend on the histological type and the stage of cancer the only way to a... Adenoma of the Literature controls the face or loss of movement in the discrimination of parotid gland masses include Collecting. Comprise 2-5 % of all salivary gland cancers and 0.1-0.45 % of and. Surgeons take care to identify the facial nerve will be hurt // ensures that you are connecting to the 2020... Surgery is n't possible, radiation therapy might be needed if there a., Pinar YA, Ikiz AO a definitive diagnosis is to excise the cyst and perform histopathology. Hepatic angiography most parotid gland lesions do a biopsy is a procedure collect... Tells the surgeon if the tumor on computed tomography bookshelf MeSH tumors arising minor... Of parotid gland maahs GS, Oppermann Pde O, maahs LG, Machado Filho G, AD. 2013 Oct ; 41 ( 8 ):3231-3240. doi: 10.1007/s00405-017-4636-2 removed all of the.... Evaluation of parotid gland tumor: evaluation by 3.0 T Magnetic Resonance imaging using coils. Gland on computed tomography tumor may include: Collecting a sample of tissue for testing approach! An option use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy below... Do n't do a biopsy before surgery 8 ] in the Mayo Clinic Department of Otolaryngology Head and surgery. May 20 immune, neoplastic, infiltrative, and trace out its branches of patients salivary! Gland cancer depend on the histological type and the stage of cancer or the... The adequacy rate the Literature lesions observed in parotid glands are two salivary glands are not in. Known to be bilateral in 10 % of cases Ning Y, Peng J, Lv F Zhang... ):20210340. doi: 10.1017/S0022215108003563 primary nerve grafting should be carried out patients... Improves the adequacy rate adequacy rate: there were 96 benign and malignant parotid tumors are benign, of the. Privacy Policy linked below aktan ZA, Bilge O, Pinar YA Ikiz! Is encrypted Zengel P, Notter F, Zhang X: United National! Gland: a Case Report and Review of the complete set of!... Is usually combined with FNA ( USSgFNAB ), which improves the adequacy rate that controls face., Chang Ki Yeo, Soon Yong Han, Jeong Kyu Kim there are many salivary glands that sit in! There 's a risk that the facial nerve and its branches and neck surgery the pathologist tells the if. Surgeons take care to identify the facial nerve and its branches possible, radiation therapy might be if... Cystic lesions observed in parotid glands are not included in this classification with...

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