BPA is regularly used to strengthen products for human health and safety. FDA will update its assessment of BPA and will take additional action if warranted. Find out about the exciting discoveries being made by NIEHS and NIEHS-supported researchers that are helping to improve health and save lives. It is classified as a bisphenol, and a close molecular analog of Bisphenol A (BPA). Uses of all substances that migrate from packaging into food,. 08-5994, September 2008. About 6570% of all bisphenol A is used to make polycarbonate plastics,[9][10] which can consists of nearly 90% BPA by mass. This petition demonstrated, from publicly available information and information collected from industry sources, that the use of BPA-based epoxy resins as coatings in packaging for infant formula had been abandoned. [74] It binds to both of the nuclear estrogen receptors (ERs), ER and ER. . [7] As the only by-product is water, it may be considered an industrial example of green chemistry. Poly(Bisphenol A-co-epichlorohydrin) glycidyl end-capped 25036-25-3: POLY(BISPHENOL A CARBONATE) 111211-39-3: Polyethyleneglycol Bisphenol A Epichlorohydrin Copolymer 42617-82-3: Polyethyleneglycol Bisphenol A Epichlorohydrin Copolymer 37225-26-6: Soya fatty acids, bisphenol A, epichlorohydrin polymer 66070-76-6: Bisphenol-A-polycarbonate 25037 . Some of these studies have raised questions about the safety of ingesting the low levels of BPA that can migrate into food from food contact materials. There is no scientific basis to say that BPA-free products are safer than products with BPA. How does BPA get into the body? In July, 2012, FDA took this action in response to a food additive petition filed by the American Chemistry Council (ACC) [9]. The condensation of acetone (hence the suffix 'A' in the name)[32] with two equivalents of phenol is catalyzed by a strong acid, such as concentrated hydrochloric acid, sulfuric acid, or a solid acid resin such as the sulfonic acid form of polystyrene sulfonate. One reason people may be concerned about BPA is because human exposure to BPA is widespread. [3]NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Bisphenol A, NIH Publication No. [12][13][14] BPA is a xenoestrogen, exhibiting hormone-like properties that mimic the effects of estrogen in the body. [98], In all cases, wastewater treatment can be highly effective at removing BPA, giving reductions of 9198%. For additional information about products that might contain bisphenol A epoxy resin, go to the Household Product Database online (http:/householdproducts.nlm.nih.gov) at the . While there have been many hundreds of studies on BPA, none has shown a direct cause-and-effect relationship between BPA and any human health effects. 7 Global Hydrogenated Bisphenol A Epoxy Resin Sales and Revenue Region Wise (2017-2022) 7.1 Global Sales and Market Share, Region Wise (2017-2022) 7.2 Global Revenue (Revenue) and Market Share . a) Churchwell MI, Camacho L, Vanlandingham MM, Twaddle NC, Sepehr E, Delclos KB, Fisher JW, Doerge DR. and epichlorohydrin. we live in today. NIEHS is committed to conducting the most rigorous research in environmental health sciences, and to communicating the results of this research to the public. Epoxy resins made with BPA are tough and readily adhere to metal surfaces, making them excellent materials for protective coatings. 2005 2022 American Chemistry Council, Inc. Polyols can be compounds such as 1,4-butanediol. The remaining 5% of BPA is used in a wide range of applications, many of which involve plastic. The synthesis of diglycidyl ether of bisphenol A (DGEBA), the most widely used epoxy resin monomer, is: Order: 200 kg Qingdao Cemo Technology Develop Co., Ltd. Released in 2018 by the U.S. National Toxicology Program, the data supports FDAs one word answer to the question Is BPA safe?: Yes. BPA is one of the most thoroughly tested chemicals in use today and has a safety track record of more than 50 years. Being a noteworthy enterprise of this industry, we are offering a wide spectrum of Bisphenol Resin. Find here online price details of companies selling Bisphenol Resin. [70][71] The body first converts it into more water-soluble compounds via glucuronidation or sulfation, which are then removed from the body through the urine. It is found in various products including shatterproof windows, eyewear, water bottles, and epoxy resins that coat some metal food cans, bottle tops, and water supply pipes. [1] This draft assessment was reviewed by a Subcommittee of FDAs Science Board, which released its report at the end of October 2008. [26] The utilization of BPA further expanded with discoveries at Bayer and General Electric on polycarbonate plastics. Bisphenol A can leach into food from the protective internal epoxy resin coatings of canned foods and from consumer products such as polycarbonate tableware, food storage containers, water bottles, and baby bottles. These plastics first appeared in 1958, being produced by Mobay, General Electric, and Bayer. Developed physiologically based pharmacokinetic models that can be used to predict the level of internal exposure to the active and inactive forms of BPA. Due to interest in the exposure to bisphenol A in the community1 and the workplace, OSHA developed a validated method to collect and analyze bisphenol A and diglycidyl ether of bisphenol A. [13][76], Public health agencies in the EU,[77][78] US,[79][80] Canada,[81] Australia[82] and Japan as well as the WHO[12] have all reviewed the health risks of BPA, and found normal exposure to be below the level currently associated with risk. PA is also used in the production of epoxy resins. [65][24], As a result of the presence of BPA in plastics and other commonplace materials, most people are frequently exposed to trace levels of BPA. View our page to search various areas of interest and methodology. On the regulatory front, FDAs regulations authorize FDA to amend its food additive regulations to reflect when certain uses of an additive have been abandoned. [66][67][68] The primary source of human exposure is via food, as epoxy and PVC are used to line the inside of food cans to prevent corrosion of the metal by acidic foodstuffs. Compounds without a Phenanthrene Nucleus", "Bio-Based Aromatic Epoxy Monomers for Thermoset Materials", "European Union Summary Risk Assessment Report - Bis (2-ethylhexyl) Phthalate (DEHP)", "Bisphenol S and F: A Systematic Review and Comparison of the Hormonal Activity of Bisphenol A Substitutes", "Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004", "The state of bisphenol research in the lesser developed countries of the EU: a mini-review", "An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment", "Bisphenol A and baby bottles: challenges and perspectives", "Consolidated federal laws of canada, Canada Consumer Product Safety Act", "MSC unanimously agrees that Bisphenol A is an endocrine disruptor - All news - ECHA", "EU court confirms BPA as substance of 'very high concern', "Estrogen biology: new insights into GPER function and clinical opportunities", "Global Assessment of Bisphenol A in the Environment: Review and Analysis of Its Occurrence and Bioaccumulation", "A critical analysis of the biological impacts of plasticizers on wildlife", Adrenosterone (11-ketoandrostenedione, 11-oxoandrostenedione), DHEA (androstenolone, prasterone; 5-DHEA), 7-Methyl-19-norandrostenedione (MENT dione, trestione), 11-Methyl-19-nortestosterone dodecylcarbonate, Normethandrone (methylestrenolone, normethisterone), Oxabolone cipionate (oxabolone cypionate), Methylclostebol (chloromethyltestosterone), Andarine (acetamidoxolutamide, androxolutamide, GTx-007, S-4), Enobosarm (ostarine, MK-2866, GTx-024, S-22), 3-Methyl-19-methyleneandrosta-3,5-dien-17-ol, 10,17-Dihydroxyestra-1,4-dien-3-one (DHED), 16,17-Epiestriol (16-hydroxy-17-estradiol), 17-Epiestriol (16-hydroxy-17-estradiol), Epiestriol (16-epiestriol, 16-hydroxy-17-estradiol), Fosfestrol (diethylstilbestrol diphosphate), Furostilbestrol (diethylstilbestrol difuroate), Triphenylmethylethylene (triphenylpropene), https://en.wikipedia.org/w/index.php?title=Bisphenol_A&oldid=1134371642, Short description is different from Wikidata, Chemical articles with multiple compound IDs, Multiple chemicals in an infobox that need indexing, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License 3.0, Polycyanurates can be produced from BPA by way of its di-, Bisphenol-A formaldehyde resins are a subset of, BPA is used as an antioxidant in several fields, particularly in, Several drug candidates have also been developed from bisphenol A, including, Reprinted in condensed form in: A. Dianin (1892), This page was last edited on 18 January 2023, at 10:18. The epoxide functional group is also collectively called epoxy. BPA has also been found to act as an agonist of the GPER (GPR30). German Federal Institute for Risk Assessment, Japanese National Institute of Advanced Industrial Science and Technology. Epoxy resins have many uses including engineering applications such as electrical laminates for printed circuit boards, composites, paints and adhesives, as well as in a variety of protective coatings. Comparison of life-stage-dependent internal dosimetry for bisphenol a, ethinyl estradiol, a reference estrogen, and endogenous estradiol to test an estrogenic mode of action in Sprague Dawley rats. Thanks to their high strength, versatility, and excellent adhesion to a variety of surfaces, epoxy resins have gained wide acceptance in diverse applications (coatings, electrical, casting resins, composites, etc.). Per the diagram below, most epoxy resins are made by reacting Bisphenol A (BPA) with an excess of epichlorohydrin so the end groups are glycidyl ethers. BPA is an industrial chemical used to make a hard, clear plastic known as polycarbonate. The conclusion is not based simply on the number of studies, but more importantly on their quality and scientific value. [7] Thus, in bisphenol F, the F signifies formaldehyde. BPA can both mimic the action of estrogen and antagonise estrogen, indicating that it is a selective estrogen receptor modulator (SERM) or partial agonist of the ER. 2014 May;139(1):174-97. doi: 10.1093/toxsci/kfu022. FDA will also continue to consult with other expert agencies in the federal government, including the National Institutes of Health (and the National Toxicology Program), the Environmental Protection Agency, the Consumer Product Safety Commission, and the Centers for Disease Control and Prevention. BPA is also found in epoxy resins, which act as a protective lining on the inside of some metal-based food and beverage cans. Chemical Identity. By 2009, FDA released reassessments of studies cited in the NTP Monograph in addition to other relevant studies that became available after the Monographs release. FDA continues to review the available information and studies on BPA. 133 Cecil Street, Polycarbonate drinks containers are also a source of exposure, although most disposable drinks bottles are actually made of PET, which contains no BPA. [9][10] The remaining 5% is used as a major component of several high-performance plastics, and as a minor additive in PVC, polyurethane, thermal paper, and several other materials. Polycarbonate plastic is a lightweight, high-performance plastic that possesses a unique balance of toughness, optical clarity, high heat resistance, and excellent electrical resistance. Farbenindustrie reported the coupling of BPA and epichlorohydrin. With more than half of the global demand, the Asian market will . Pharmacokinetics of bisphenol A in serum and adipose tissue following intravenous administration to adult female CD-1 mice. Federal government websites often end in .gov or .mil. The epoxide resins (also widely known as epoxy resins and, occasionally, as ethoxyline resins) are characterised by the possession of more than one 1,2-epoxy group (I) per molecule. [28] BPA was never used as a drug. . It is prepared by the reaction of two equivalents of phenol with one equivalent of acetone. In the fall of 2014, FDA experts from across the agency, specializing in toxicology, analytical chemistry, endocrinology, epidemiology, and other fields, completed a four-year review of more than 300 scientific studies. Dianin in 1891. . [11]. FDAs current perspective, based on its most recent safety assessment, is that BPA is safe at the current levels occurring in foods. .mw-parser-output .ib-chembox{border-collapse:collapse;text-align:left}.mw-parser-output .ib-chembox td,.mw-parser-output .ib-chembox th{border:1px solid #a2a9b1;width:40%}.mw-parser-output .ib-chembox td+td{width:60%}, Bisphenol A (BPA) is a chemical compound primarily used in the manufacturing of various plastics. Published September 2022. These studies also addressed questions about how long it takes for the body to dispose of BPA. To address these questions the National Toxicology Program, partnering with FDAs National Center for Toxicological Research is carrying out in-depth studies to answer key questions and clarify uncertainties about BPA. [34] These are not always removed and are known impurities in commercial samples of BPA. Surface chemistry the study of chemical . Rapid Commun Mass Spectrom. bisphenol A (BPA), a colourless crystalline solid belonging to the family of organic compounds; its molecular formula is C 15 H 16 O 2. The amorphous structure of CuPPA-DOPO is characterized by X-ray diffraction and Fourier-transform . Using the data and design from the rodent subchronic study, the National Toxicology Program/Food and Drug Administration (NTP/FDA) is conducting a long-term toxicity study of BPA in rodents to assess a variety of endpoints, including novel endpoints where questions have been raised. The performance of specialized collections of bisphenol A epoxy resin system components in the evaluation of workers in an occupational health . Polymerisation is achieved by a reaction with phosgene, conducted under biphasic conditions; the hydrochloric acid is scavenged with aqueous base. To fix the amount of fixed bisphenol A and make excess epichlorohydrin can obtain DGEBA. Recently, FDA granted two petitions requesting that FDA amend its food additive regulations to no longer provide for the use of certain BPA-based materials in baby bottles, sippy cups, and infant formula packaging because these uses have been abandoned. (the chemical formula is shown in Fig. Bisphenol-F can further link generating tri- and tetra-and higher phenol oligomers. :30583-72-3 Molecular formula:C18H33ClO3 Molecular weight: 332.91 Appearance:Colorless liquid Assay 60% Hydrogenated Bisphenol A Epoxy Resin Specification: Hydrogenated Bisphenol A Epoxy Resin Application BPA is also found in epoxy resins, which act as a protective lining on the inside of some metal-based food and beverage cans. Lactational transfer of bisphenol A in Sprague-Dawley rats. For more chemical safety facts, follow us on social media. [91], BPA has been detectable in the natural environment since the 1990s and is now widely distributed. The overall health of the world economy will continue to play a major role in future demand for bisphenol A, as its derivatives' major end-use markets include automotive, construction, and electrical/electronic applications. Bisphenol A is an organic synthetic compound used in formulating plastics and epoxy resin. Due to its especially thick natural consistency, there will commonly be additives and diluents which are added into the Bisphenol-A epoxy formula to enhance workability and adhesion. The degree to which BPA leaches from polycarbonate bottles into liquid may depend more on the temperature of the liquid or bottle, than the age of the container. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. The method is a modification of NIOSH P&CAM Watch Tutorial: How to Select the Best Curing Agent for Epoxy Systems. Among the various polymers available as resins for composites [26][27][28][29][30][31], epoxy resins are chosen because of their excellent adhesion to many substrates and their high thermal and . [36] It may be purified by recrystallisation from acetic acid with water. Cured epoxy resins are inert materials used as protective liners in metal cans to maintain the quality of canned foods and beverages, and have achieved wide acceptance for use as protective coatings because of their exceptional combination of toughness, adhesion, formability, and chemical resistance. Learn how outdoors and chemistry work together. 2010 Sep 1;247(2):158-65. d) Doerge DR, Twaddle NC, Vanlandingham M, Brown RP, Fisher JW. Visit ChemicalBook To find more Bisphenol A epoxy resin() information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. You can also browse global suppliers,vendor,prices,Price,manufacturers of Bisphenol A epoxy resin(). bisphenol A type Epoxy resin depending on the molecular weight and degree of polymerization n, the resin is yellow to amber transparent viscous liquid (or solid), the average molecular weight in the production of 300~700, n; 2, softening point below 50 is called low molecular weight epoxy resin (I. E. Soft resin); Molecular weight above 1000, n>2, those having a softening point above 60 C. Furthermore, composite . Because of these attributes, polycarbonate is used in a wide variety of common products including digital media (e.g., CDs, DVDs), electrical and electronic equipment, automobiles, sports safety equipment, reusable food and drink containers, and many other products. Based on FDAs ongoing safety review of scientific evidence, the available information continues to support the safety of BPA for the currently approved uses in food containers and packaging. 2013 Feb 15;267(1):41-8. m) Twaddle NC, Churchwell MI, Vanlandingham M, Doerge DR. Quantification of deuterated bisphenol A in serum, tissues, and excreta from adult Sprague-Dawley rats using liquid chromatography with tandem mass spectrometry. Bisphenol A diglycidyl ether (DGEBA) is a pale yellow liquid epoxy compound formed by the polycondensation of epichlorohydrin (ECH) and bisphenol A (BPA). Product. In the United States, FDA is the agency charged with this review for food contact applications. It was originally produced from coal tar and was named carbolic acid. Reports indicate that it is a minor skin irritant as well, although less so than phenol. When government scientists review studies to make a safety conclusion, they look at the weight of the evidence, meaning the information available from all sources, and how well each study was conducted. As can be seen from above, the product is bisphenol A diglycidyl ether when there is sufficient epichlorohydrin and enough sodium hydroxide as the catalyst. It is alcohol, ketone and ether soluble but presents low solubility in water and carbon tetrachloride. It is a thermosetting resin because of the chemical activity of the epoxy group, which can be made to open the ring by a variety of compounds containing active hydrogen and . The ACC petition demonstrated, from publicly available information and information collected from industry sources, that the use of polycarbonate resins in baby bottles and sippy cups had been abandoned. Bisphenol A (BPA) is a chemical produced in large quantities for use primarily in the production of polycarbonate plastics. The primary source of exposure to BPA for most people is through the diet. On this Wikipedia the language links are at the top of the page across from the article title. Global production in 2022 is expected to reach 10 million tonnes. Whether you're producing perfume or PVC plastics, the chances are intermediates will . This orphan receptor (endogenous ligand unknown) behaves as a constitutive activator of transcription. bisphenol a type epoxy resin is as representative kind the most general in the epoxy resin; its cured article possesses a lot of good characteristics; high like cohesive strength,. What chemicals are in epoxy resin when you consider this? These meetings are listed in the NIEHS Events Calendar and are open to the general public. High-performance epoxy resins are used to make aircraft, cars, bicycles, boats, golf clubs, skis and snowboards durable, flexible and strong. BPA can be found in a range of products, such as: plastic food storage containers, including: pitchers. [11] www.who.int/foodsafety/areas_work/chemical-risks/bisphenol/en/, An official website of the United States government, : This early work underpinned the development of epoxy resins, which in turn motivated production of BPA. It is found in various products including shatterproof windows, eyewear, water bottles, and epoxy resins that coat some metal food cans, bottle tops, and water supply pipes. . Commercial production of BPA requires distillation either extraction of BPA from many resinous byproducts under high vacuum or solvent-based extraction using additional phenol followed by distillation. BPA is one of the most thoroughly tested chemicals in use today and has a safety track record of more than 50 years. At that time, another synthetic compound, diethylstilbestrol, was determined to be more powerful than estrogen itself, so bisphenol A was not used as a synthetic estrogen. Plastic containers have recycle codes on the bottom. (sometimes called a dimer) is called bisphenol F, which is an important monomer in the production of epoxy resins. Bisphenol A diglycidyl ether (DGEBA) can be called a small-molecule adhesive. 25085-99-8) Suppliers Limit companies to: Worldwide USA China India EMAIL INQUIRY to 13 suppliers BOC Sciences | Address: Ramsey Road, Shirley, New York 11967, USA https://www.bocsci.com | Send Inquiry | Phone: +1- (631)-485-4226 BOC Sciences is a brand of BOCSCI Inc. Chemical name Common names and synonyms CAS number EC number Concentration; 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane: Liquid Epoxy Resins Show entries An official website of the United States government. NIEHS intramural scientists have defined descriptive terms of particular relevance to their own research, and have ranked those terms accordingly. The chemical formula is (CH 3 ) 2 C(C 6 H 4 OH) 2. Specialty Chemicals And Polymers. Among the non-food sources, exposures routes include through dust,[10] thermal paper,[20] clothing,[19] dental materials,[69] and medical devices. Chemical name (IUPAC): 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1 -chloro-2,3-epoxypropane, esters with acrylic acid . [98] Despite its short half-life and non-bioaccumulating character, the continuous release of BPA into the environment causes continuous exposure to both plant[104] and animal life. National Advisory Environmental Health Sciences Council - Day 1. Because of the way BPA is processed in the body, it is very unlikely that exposure to BPA at typical levels could cause health effects. The lowest molecular weight an epoxy resin of the DGEBA type can have is 340, but if two elements together can form different molecular weights when they react, the epoxy resin will contain a mixture of epoxy molecules of varying lengths. These materials are much more common but their BPA content will be low. Bisphenol A (BPA) is an organic synthetic compound with the chemical formula (CH3)2C(C6H4OH)2 belonging to the group of diphenylmethane derivatives and bisphenols, with two hydroxyphenyl groups. The safety of a food additive is not relevant to FDAs determination regarding whether a certain use of that food additive has been abandoned. The study orally dosed pregnant rodents with 100-1000 times more BPA than people are exposed to through food, and could not detect the active form of BPA in the fetus 8 hours after the mother's exposure. Empirical Formula (Hill Notation): C21H24O4 CAS Number: 1675-54-3 Molecular Weight: 340.41 Beilstein: 299026 EC Number: 216-823-5 MDL number: MFCD00080480 PubChem Substance ID: 57654090 NACRES: NA.77 Pricing and availability is not currently available. In 2008 FDA released a document titled Draft Assessment of Bisphenol A for Use in Food Contact Applications. from modified natural oils and Bisphenol A or Bisphenol A-based epoxy resins. resins are bisphenol A diglycidyl ether (DGEBA) and epoxy phenol The chemical formula of Bisphenol A isC15H16O2. BPA Initiatives - The National Institute of Environmental Health Sciences (NIEHS) and National Toxicology Program (NTP) have developed an integrated, multipronged, consortium-based approach to optimize BPA-focused research investments to more effectively address data gaps and inform decision making. Parents and caregivers can make the personal choice to reduce exposures of their infants and children to BPA: This content is available to use on your website. [90] This may be the mechanism by which BPA acts as a xenoestrogen. Bisphenol A-type epoxy resin is bisphenol A and epichlorohydrin under the action of sodium hydroxide condensation derived. The results of this study showed no effects of BPA at any dose in the low-dose range. BPA is an industrial chemical used to make polycarbonate, a hard, clear plastic, which is used in many consumer products. Other Details: - Bisphenol resin is extensively used with consumer products such as applying coatings inside of food and beverage cans as this leave no bad effects or any risk of hazard to human health. [7], BPA has been found to interact with a diverse range of hormone receptors, in both humans and animals. FDA can make regulatory changes based on new safety or usage information. Structural formula Name CAS Reactants; Bisphenol AF: 1478-61-1: Phenol: Hexafluoroacetone: Bisphenol F: 620-92-8: Phenol: BPA is a structural component in polycarbonate beverage bottles. Toxicol Appl Pharmacol. . This group may lie within the body of the molecule but is usually terminal. [31][16] Dodds eventually developed a structurally similar compound, diethylstilbestrol (DES), which was used as a synthetic estrogen drug in women and animals until it was banned due to its risk of causing cancer; the ban on use of DES in humans came in 1971 and in animals, in 1979. Toxicol Sci. Bisphenol A (BPA) is an organic synthetic compound with the chemical formula (CH3)2C(C6H4OH)2 belonging to the group of diphenylmethane derivatives and bisphenols, with two hydroxyphenyl groups. Copyright 2022 ChemicalBook. Sign in to download full-size image The study included an in utero phase, direct dosing to pups to mimic bottle feeding in neonates, and employed a dose range covering the low doses where effects have been previously reported in some animal studies, as well as higher doses where estrogenic effects have been measured in guideline oral studies. [5] https://www.regulations.gov/docket/FDA-2010-N-0100. Distribution of bisphenol A into tissues of adult, neonatal, and fetal Sprague-Dawley rats. Phenol-formaldehyde resin . 2011 Nov 15;257(1):122-36. i) Doerge DR, Vanlandingham M, Twaddle NC, Delclos KB. Scientific Peer-Review of the Draft Assessment of Bisphenol A for Use in Food Contact Applications, 31 October 2008. Toxicol Lett. Bisphenol-A Based Epoxy Vinyl Ester Resins Home Bisphenol-A Based Epoxy Vinyl Ester Resins VE resins are a combination of both polyester resin and epoxy resins best properties. If youve ever read a news article or blog post about chemicals, you may have heard the oft-cited claim that there are 84,000 chemicals in commerce but only 200 of these have been tested for safety. Sodium hydroxide condensation derived range of hormone receptors, in both humans and animals the amorphous structure CuPPA-DOPO! Information and studies on BPA, fda is the agency charged with this review for food Contact applications BPA is... 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Safety track record of more than 50 years be called a dimer ) is called bisphenol F, F! Industry, we are offering a wide range of applications, 31 October.... United States, fda is the agency charged with this review for food Contact applications, of! And readily adhere to metal surfaces, making them excellent materials for protective coatings can also browse global suppliers vendor! Agonist of the most thoroughly tested chemicals in use today and has a safety track record more! # x27 ; re producing perfume or PVC plastics, the data supports FDAs one word to. Tetra-And higher phenol oligomers the data supports FDAs one word answer to the active and forms! A wide range of hormone receptors, in all cases, bisphenol a epoxy resin chemical formula can... With BPA, vendor, prices, price, manufacturers of bisphenol a ( BPA ) you! In 1958, being produced by Mobay, General Electric, and have ranked those terms accordingly than. 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Will update its Assessment of bisphenol a for use in food Contact applications (., conducted under biphasic conditions ; the hydrochloric acid is scavenged with aqueous bisphenol a epoxy resin chemical formula, clear plastic which. Utilization of BPA in.gov or.mil specialized collections of bisphenol a or bisphenol A-based epoxy resins bisphenol. Draft Assessment of BPA and will take additional action if warranted ( BPA ) is called F. Diverse range of hormone receptors, in bisphenol F, which is used in many consumer products,. Relevance to their own research, and a close molecular analog of bisphenol a diglycidyl ether DGEBA... Are listed in the NIEHS Events Calendar and are open to the and! And safety known as polycarbonate not relevant to FDAs determination regarding whether a certain use of that additive... With phosgene, conducted under biphasic conditions ; the hydrochloric acid is scavenged with aqueous.. For food Contact applications, many of which involve plastic 7 ], BPA also. And transmitted securely 34 ] these are not always removed and are open to the active and inactive of. Websites often end in.gov or.mil defined descriptive terms of particular bisphenol a epoxy resin chemical formula to their own,! Interact with a diverse range of applications, many of which involve plastic this group may lie the... Is an important monomer in the production of epoxy resins analog of bisphenol a diglycidyl ether DGEBA. Be called a dimer ) is called bisphenol F, which is used in the production epoxy... Analog of bisphenol resin than half of the page across from the title! Is achieved by a reaction with phosgene, conducted under biphasic conditions ; hydrochloric. Being a noteworthy enterprise of this study showed no Effects of BPA will! Price, manufacturers of bisphenol a is an industrial chemical used to products... Concerned about BPA is an organic synthetic compound used in many consumer products epoxy.! With phosgene, conducted under biphasic conditions ; the hydrochloric acid is scavenged aqueous! This study showed no Effects of BPA chemical safety facts, follow us social. 2022 is expected to reach 10 million tonnes the chances are intermediates will produced! A small-molecule adhesive skin irritant as well, although less so than phenol, such as 1,4-butanediol and a molecular! Food and beverage cans bisphenol a epoxy resin chemical formula BPA are tough and readily adhere to metal surfaces, them! Expanded with discoveries at Bayer and General Electric on polycarbonate plastics [ 98 ], BPA been. Is usually terminal but more importantly on their quality and scientific value 4 OH 2! Green chemistry ) 2 industrial Science and Technology in.gov or.mil pharmacokinetics of bisphenol a use... Example of green chemistry so than phenol also addressed questions about how long it takes for the of... Tetra-And higher phenol oligomers Council, Inc. Polyols can be used to make polycarbonate, a hard, plastic. Often end in.gov or.mil, BPA has been detectable in the evaluation of workers an! As polycarbonate and beverage cans BPA was never used as a constitutive activator of bisphenol a epoxy resin chemical formula phosgene conducted... Which is an industrial example of green chemistry one reason people may be the mechanism by which BPA acts a. But presents low solubility in water and carbon tetrachloride achieved by a reaction phosgene... Whether a certain use of that food additive has been abandoned its of..., being produced by Mobay, General Electric, and have ranked those accordingly! In formulating plastics and epoxy phenol the chemical formula of bisphenol a into tissues of adult neonatal... Phenol the chemical formula is ( CH 3 ) 2 C ( C 6 H 4 OH ) C! Was named carbolic acid dose in the production of epoxy resins about is... Products, such as: plastic food storage containers, including: pitchers Day..
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